Who Uses Semaglutide
Weight Loss
Reduces appetite so you eat less and lose weight steadily week over week.
Appetite Control
Ends the food noise and constant cravings that make dieting feel impossible.
Blood Sugar
Improves insulin sensitivity — originally developed as a treatment for type 2 diabetes.
1
Reconstitution
Vial Size & Water Guide
| Vial Size | Bacteriostatic Water | Concentration | 0.25mg Dose → Draw To |
|---|---|---|---|
| 10 mg | Add 2 mL | 0.05 mg per unit | 5 units on the syringe |
| 20 mg | Add 4 mL | 0.05 mg per unit | 5 units on the syringe |
| 30 mg | Add 6 mL | 0.05 mg per unit | 5 units on the syringe |
The concentration per unit is the same regardless of which vial size you buy — larger vials simply last longer. Tilt the vial and inject bacteriostatic water slowly down the glass wall. Swirl gently — do not shake. Refrigerate immediately after mixing. Dose once weekly on the same day.
Watch: How to Reconstitute a Peptide Vial
Note: water amounts vary by compound — always follow the reconstitution amounts listed in the table above for Semaglutide.
2
How to Inject
Method
SubQ (Subcutaneous)
Into the fat layer just under the skin
Needle Angle
45°
Pinch skin, insert at a shallow angle
Preferred Sites
Belly, thigh, or upper arm
Rotate sites each weekly injection
Timing
Once per week
Same day each week, any time of day
3
Your Protocol
Slow & Steady
0.5 mg
max weekly (after titration)
Best For
Sensitive individuals, gentle weight loss, minimal side effects
Draw at Maintenance
0.5mg → draw to 10 units
(all vial sizes)
(all vial sizes)
Titration
Wk 1–4: 0.25mg → Wk 5+: 0.5mg/week
Most Popular
Suggested
1 mg
max weekly (after titration)
Best For
Most users — community standard for steady, consistent fat loss
Draw at Maintenance
1mg → draw to 20 units
(all vial sizes)
(all vial sizes)
Titration
Wk 1–4: 0.25mg → Wk 5–8: 0.5mg → Wk 9+: 1mg/week
Aggressive but Safe
2 mg
max weekly (after titration)
✓ Maximum clinical dose — well-studied and safe for most people
Best For
Experienced users, significant weight loss targets, or non-responders at lower doses
Draw at Maintenance
2mg → draw to 40 units
(all vial sizes)
(all vial sizes)
Titration
Wk 1–4: 0.25mg → Wk 5–8: 0.5mg → Wk 9–12: 1mg → Wk 13+: 2mg
Titration Comparison — All 3 Protocols Side by Side (Weekly Dose)
| Week | Slow & Steady | Suggested | Aggressive |
|---|---|---|---|
| Week 1–4 | 0.25 mg | 0.25 mg | 0.25 mg |
| Week 5–8 | 0.5 mg | 0.5 mg | 0.5 mg |
| Week 9–12 | 0.5 mg | 1 mg | 1 mg |
| Week 13+ | 0.5 mg | 1 mg | 2 mg |
What to Expect
- Weeks 1–2: Reduced appetite and hunger signals. Food cravings begin to drop noticeably.
- Weeks 4–8: Consistent weekly weight loss, improved satiety, and better blood sugar regulation throughout the day.
- Weeks 8–16: Progressive body composition improvement. Keep protein high (0.8–1g per lb bodyweight) to protect muscle while fat is lost.
Do
- Titrate slowly — skipping ahead causes severe nausea
- Keep protein high to preserve muscle during weight loss
- Stay hydrated throughout the cycle
- Track weekly weight same day and time for consistency
Don't
- Skip the titration schedule — nausea will be severe
- Stop eating entirely — maintain a reasonable caloric deficit
- Use if you have a family history of medullary thyroid cancer
- Shake the vial — swirl gently only
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Supplies You'll Need
Insulin Syringes (for injection)
Use one fresh syringe per injection. 29–31 gauge ensures minimal discomfort for SubQ use.
Reconstitution Syringe
For mixing only — do NOT use for injection.
Alcohol Swabs
Wipe the vial top and injection site before every use.